splice-switching oligonucleotides

Spanish translation: oligonucleótidos moduladores de (corte y) empalme

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:splice-switching oligonucleotides
Spanish translation:oligonucleótidos moduladores de (corte y) empalme
Entered by: David Balayla

11:13 Apr 17, 2020
English to Spanish translations [PRO]
Science - Biology (-tech,-chem,micro-)
English term or phrase: splice-switching oligonucleotides
The use of synthetic oligonucleotides as therapeutic agents has witnessed remarkable progress over recent decades leading to the development of molecules acting by diverse mechanisms including RNase H activating gapmers, splice switching oligonucleotides, microRNA inhibitors, siRNA or aptamers.
David Balayla
Spain
Local time: 06:49
oligonucleótidos moduladores de (corte y) empalme
Explanation:
To
date, splicing-switch oligonucleotides (SSOs) were used as
a means of drugs to modulate RNA splicing in cancer. SSOs
are short, synthetic, antisense, modified nucleic acids and
designed to base-pair and create a steric block to the binding
of splicing factors to the pre-mRNA [66].
https://www.researchgate.net/publication/329098813_Function_...
Selected response from:

Kepa S S O (X)
Colombia
Local time: 00:49
Grading comment
gracias Kepa
4 KudoZ points were awarded for this answer



Summary of answers provided
3 +2oligonucleótidos que modifican el splicing
liz askew
3oligonucleótidos moduladores de (corte y) empalme
Kepa S S O (X)


  

Answers


28 mins   confidence: Answerer confidence 3/5Answerer confidence 3/5 peer agreement (net): +2
oligonucleótidos que modifican el splicing


Explanation:


https://repositorio.uam.es › handle › yuste...
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by P Yuste Checa - ‎2015 - ‎Related articles
Oligonucleóticos antisentido que modifican el splicing (Splice switching oligonucleofides). Tm: Temperatura de melfing. TMEM165: Proteína transmembrana ...

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Note added at 29 mins (2020-04-17 11:43:15 GMT)
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https://docplayer.es › 12244398-Desarroll...
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... nuclear ribonucleoproteins) SPR: Sepiapterina reductasa SSO: Oligonucleóticos antisentido que modifican el splicing (Splice switching oligonucleotides) Tm: ...

liz askew
United Kingdom
Local time: 05:49
Does not meet criteria
Native speaker of: Native in EnglishEnglish
PRO pts in category: 52
Notes to answerer
Asker: thanks for the help Liz


Peer comments on this answer (and responses from the answerer)
agree  Mónica Algazi
25 mins

agree  abe(L)solano
2 hrs
Login to enter a peer comment (or grade)

12 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
oligonucleótidos moduladores de (corte y) empalme


Explanation:
To
date, splicing-switch oligonucleotides (SSOs) were used as
a means of drugs to modulate RNA splicing in cancer. SSOs
are short, synthetic, antisense, modified nucleic acids and
designed to base-pair and create a steric block to the binding
of splicing factors to the pre-mRNA [66].
https://www.researchgate.net/publication/329098813_Function_...

Kepa S S O (X)
Colombia
Local time: 00:49
Meets criteria
Specializes in field
Native speaker of: Spanish
PRO pts in category: 24
Grading comment
gracias Kepa
Login to enter a peer comment (or grade)



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