Glossary entry

Spanish term or phrase:

refractaría

English translation:

refractory to

    The asker opted for community grading. The question was closed on 2009-07-13 00:54:04 based on peer agreement (or, if there were too few peer comments, asker preference.)
Jul 9, 2009 23:36
14 yrs ago
1 viewer *
Spanish term

refractaría

Spanish to English Medical Medical: Health Care
paciente ***refractaria*** a anti-TNF y MTX

Discussion

Richard McDorman Jul 10, 2009:
You're welcome :) Those tricky accent marks have tripped me up before!
Consult Couture (asker) Jul 9, 2009:
No accent indeed That makes a lot more sense now. Thank you!
Omar Lima Quintana Jul 9, 2009:
Suzanne: Some more context available?

Proposed translations

+5
3 mins
Selected

refractory to

Hope this helps!



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Note added at 3 mins (2009-07-09 23:40:30 GMT)
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http://dictionary.reference.com/browse/refractory

2. resisting ordinary methods of treatment.


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Note added at 6 mins (2009-07-09 23:43:28 GMT)
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http://www.ingentaconnect.com/content/els/07507658/2003/0000...

http://www.bloodline.net/articles/blr_1_1_witzig.html

About the same time as the study just discussed, another study was conducted to approach the question of whether yttrium was adding anything to standard therapy. This study took patients who had undergone Rituxan therapy but had failed it. Failure of Rituxan therapy was defined in two ways: a patient responded, but the response lasted less than six months, or a patient was simply refractory to the therapy.

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Note added at 8 mins (2009-07-09 23:45:17 GMT)
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http://gateway.nlm.nih.gov/MeetingAbstracts/ma?f=102246753.h...

Disseminated infection caused by Blastoschizomyces capitatus is frequently fatal in granulocytopenic patients, despite the administration of Amphotericin B. The cause of this refractoriness is not known. We study four isolates of B. capitatus isolated from granulocytopenic patients with disseminated blastoschizomycosis that were refractory to Amphotericin B. Materials andMETHODS: MICs of Amphotericin B were determined by using the standard microdilution method approved by NCCLS. Two different inocula ...

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Note added at 3 days1 hr (2009-07-13 01:13:07 GMT) Post-grading
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Many thanks to all!!
Peer comment(s):

agree Leda Roche : refractaria/o without accent in Spanish
1 hr
Thank you very much Denise :)
agree ARS54 : ...Es eso, :) See: http://www.google.it/search?hl=it&q="patients refractory to"... *Resistant* is a slightly different concept. Anna Rosa
2 hrs
Thank you very much ARS54
agree Panagiotis Andrias (X) : Agree with AR. See...OS and PFS did not differ significantly between platinum-resistant and platinum-refractory disease (p = 0.799 and p = 0.322 respectively) or according to ... linkinghub.elsevier.com/retrieve/pii/S0090825806007141 -
8 hrs
Thank you very much Panagiotis :)
agree liz askew : http://209.85.229.132/search?q=cache:bpy-ABrXauUJ:www.proz.c...
9 hrs
Thank you very much liz:)
agree Susana Sherman
17 hrs
Thank you very much Susana :)
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Selected automatically based on peer agreement."
+4
15 mins

resistant to

Note: The original text does not appear to have an accent over the i. I think that the word in the original is therefore "refractaria", and not "refractaría." This seems to make more sense, given the context.

re·frac·ta·rio -ria

adj.
(1) [physics] refractory, heat-resistant
(2) [figurative] (opuesto) refractory, resistant

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Note added at 16 mins (2009-07-09 23:53:01 GMT)
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http://education.yahoo.com/reference/dict_en_es/spanish/refr...

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Note added at 19 mins (2009-07-09 23:55:34 GMT)
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Note: Perhaps you can check the original carefully, to see if the word ending is -ia or -ía, as there is a discrepancy between the way the word appears in the question and in the context sentence you provided.
Peer comment(s):

agree Pilar Ibarburu : I agree with Richard
25 mins
Thank you very much! :)
agree Alejandra Garza : That's how I use it.
1 hr
Thank you.
agree Gabriela Mejías : That's how I use it too. Saludos, Richard. :)
2 hrs
Thanks, Gabriela.
agree Anandrade
19 hrs
Thank you.
Something went wrong...
6 hrs

lack of response/unresponsive

Although "refractory" is commonly used in English. "Resistant" is too strong a word to use in this case

A definition of "refractorio/a"- Relativo a la falta de respuesta de una enfermedad a un determinado tratamiento
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Reference comments

9 hrs
Reference:

English term or phrase: MTX-refractory
Spanish translation: refractaria al metotrexate
Entered by: Cecilia Palluzzi
Options:
- Contribute to this entry

18:28 Jan 18, 2006 Login or register (free) for more options.
English to Spanish translations [PRO]
Medical - Medical: Pharmaceuticals / Rheumatology
English term or phrase: MTX-refractory
Complete sentence: Inhibition of structural damage at 2 years in MTX-refractory established RA.
Son datos de un estudio sobre la aplicxacion de cierto medicamento en el tratamiento de AR.
También necesito corroborar el uso de naive en "MTX-naive".
Gracias!!!
Cecilia Palluzzi
Argentina

Local time: 02:43
refractaria al metotrexate
Explanation:
Methotrexate is a disease-modifying anti-rheumatic drug (DMARD). MTX-naive is a patient who has never used methotrexate
Something went wrong...
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