Jun 12, 2011 04:25
12 yrs ago
Japanese term

形成しても

Japanese to English Medical Medical (general)
Explanation: Topic: Breast cancer

Sentence: また、間質浸潤が起こり浸潤性腫瘤を[形成しても]、浸潤性腫瘤の内部や浸潤性腫瘤からかなり離れた乳管にまで乳癌の乳管内進展が拡大している場合がある

I've struggled with this sentence for a few days...particularly the logic of the connection ”しても”

If anyone thinks this is straightforward, please give me some clues.

Thank you.
References
FYI

Discussion

Joss Ky (asker) Jun 17, 2011:
Thank you Yumico for your suggestions! I always want to paste the entire section here for discussion, but I'm limited by confidentiality rules unfortunately. I'm sorry that makes it a lot harder to answer!
Yumico Tanaka (X) Jun 12, 2011:
You have to study the sentences before and after. You don't seem to understand the content of the field. I am not an expert either, but there may be some phrases that show the relavance. A connotation I suspect hidden here is "already" but you don't give any other contexts before and after. I suggest you ask your agent or client.

Proposed translations

+1
2 hrs
Selected

even though (A) and formed (B)

o.k. I will post my opinion this time as a suggestion to the answer.

suggestions for:
(A)
it has invaded into the interstitium
an interstitial extension has occured

(B)
a infiltrating mass
a infiltrative mass

(You need to do research to find best words to make your choice or find better words for them)

I need to see several sentences prior to this to be sure but I assume this is talking about a behaviour of non-infiltrating (or non-invasive) intraductal mammary carcinoma, which is considered to occurs in very early stage of mammary carcinoma where cancer tissue is confined to inside the ducts, still not yet broken through the basement membrane and enter the interstitial space. So when the cancer tissue break through the membrane and enter the interstitium, there is no barrier (or something hinders the extension of the cancer cells), they grow as a mass. Here is my biggest assumption (and it might get clearer if I read all of Mr cinefil's references), when it came to the point at which those cancer tissue spread to interstitium, they don't bother growing along inside the ductules, and prefer or easier to grow in the interstitium, or so one might want to think. But here the sentence is telling you that it is not the case, but you still see great growth of cancer tissue inside ducts (inside the ducts of the mass itself and also) further extending out from the mass, through the duct system (because they run long distance).

Well, this is my take on the thingy, and it takes many more hours of readings to be sure of the whole subject for me, so I rest here and wish you the best and good luck !
Peer comment(s):

agree Mami Yamaguchi
5 mins
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Thank you so much for your opinion--it makes sense now. "
+2
1 hr

Although/even (it is) derived from

形成し[ても]

ても means 'even though' here

The whole sentence here refers to the origin of invasive breast cancer. It may form from the stroma, or develop as a result of intraductal progression.
Peer comment(s):

agree Mami Yamaguchi
1 hr
agree Soonthon LUPKITARO(Ph.D.)
19 hrs
Something went wrong...
+2
11 hrs

even if it is formed

This sentence describes ductal spread of epithelial cancers (or one type of those) of the breast.

The implication is: It mainly spread through the ducts, but in case of interstitial infiltration (not that rare) and even if infiltrative mass is formed (it is rare), ~~~

Good luck, Joss!
Peer comment(s):

agree Y. K.
21 hrs
Thanks!
agree Mami Yamaguchi : As for the formation of a infiltrative mass,I think your suggestion is the same as Chris.
1 day 5 hrs
Thanks!
Something went wrong...

Reference comments

17 mins
Reference:

FYI

Note from asker:
Thank you so much. http://homepage3.nifty.com/francis/data/22/kurozumi.pdf was particularly useful.
Peer comments on this reference comment:

agree Mami Yamaguchi
1 day 20 hrs
ありがとうございます。
Something went wrong...
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