Larisa Horback Feb 13, 2016:

No problem. It's insane to know everything..

Erzsébet Czopyk Feb 13, 2016:

@Evgeni, @Larisa thank you very much (I mean you both) for this clarification/your contribution

Evgeni Kushch Feb 13, 2016:

еще также:

s histological
findings

Liver biopsy findings

Biopsy findings and clinical correlations

Evgeni Kushch Feb 13, 2016:

Findings тоже встречается, но вот больше, как я и писал, в целенаправленном поиске

Physical
findings may be normal, but sometimes hepatomegaly, occasionally
painful, splenomegaly and, when frank cirrhosis has developed,
signs and symptoms of chronic liver disease like palmar
erythema and spider naevi may be found.

Acute onset of AIH does exist (about 25% of patients); there are two different clinical entities (the acute
exacerbation of chronic AIH and the true acute AIH without histological findings of chronic liver disease);

Some patients within AIH spectrum have characteristics of either PBC or PSC (overlap or variant forms);
though these conditions really do exist, diagnosis is usually difficult and problematic as internationally
agreed criteria are lacking; concurrent cholestatic findings require investigation for AMA and
cholangiography

The diagnosis
of large duct PSC should always be established on typical
cholangiographic findings, keeping in mind that an intrahepatic
biliary tree which simulates a sclerosing pattern can also be
observed in any liver d

In patients with an
insidious onset and gradual progression without apparent symptoms,
the diagnosis relies predominantly on laboratory findings

Evgeni Kushch Feb 13, 2016:

Все нашел, что можно было, в одной статье: In advanced stages, the clinical picture of portal hypertension dominates including ascites, oesophageal varices and portal hypertensive gastropathy, cytopenias due to hypersplenism as well as hepatic encephalopathy

Evgeni Kushch Feb 13, 2016:

Вот у меня в переводе кстати сегодня встретилось: Secondly, AIH is a very heterogeneous disease.
Like other rare diseases, clinical studies are hampered by the
limited number of patients that can be included in trials. Possibly
and more importantly, the interest of the pharmaceutical industry
to develop effective specific therapies for rare diseases is limited
due to the very restricted market for such products. The wide
heterogeneity of affected patients and clinical manifestations of
the disease limits both diagnostic and further therapeutic studies.
AIH’s age spectrum is extremely wide, it can affect small infants
and can manifest for the first time in octogenarians.

И дальше (в отвлеченном варианте "проявлений")

Indeed, approximately 25% of
patients present with an acute onset of AIH, which is phenotypically
similar to acute hepatitis cases of other causes [33,38].
However, acute presentation of AIH actually may contain two different
clinical entities.

Commonly (about one third of patients), the clinical presentation
is characterized by the presence of one or more of several
non-specific symptoms listed in Table 2 [8,11,13,18,21,29,33,
44,45].

Larisa Horback Feb 12, 2016:

I was looking for description of term in a book "Medical Surgical Nursing" and found so many medical "manifestations", so it seems like this term is very popular. I don't think that clinical picture is right term. However, it can be used when we talk about disease but not like scientific term. If i could vote for medical manifestation again I would do it. I believe author of that answer provided perfect answer.

Evgeni Kushch Feb 12, 2016:

Я вот пропустил, Андрей писал про "clinical picture", возможно он и не очень "носительский", но встречается и используется 100%

Larisa Horback Feb 12, 2016:

Thank you; you made my day:)

Evgeni Kushch Feb 12, 2016:

Вы правы Лариса, нужно больше как синонимы рассматривать :-)

Еще же есть китайский английский, шведский, норвежский, финский и пр., и пр. и пр. :-)

Хотя presented зачастую все же рассматривается как "при поступлении/при обращении/и (реже) при осмотре было выявлено/определялось", но то же ведь не всегда речь о поступлении, когда данный термин используется...

https://books.google.com.ua/books?id=C97wBQAAQBAJ&pg=PA32&lp...

Larisa Horback Feb 12, 2016:

Мне кажется еще может зависеть от страны.
Вообщем оба варианта правильно и мне кажется, что скорее всего это синонимы

Evgeni Kushch Feb 12, 2016:

Лариса, я тоже когда-то пытался разобраться, и, к своему сожалению, пришел к выводу, что данные термины перемешаны и никто особо не заморачивается :-)

В презентацию практически всегда вкладывают в первую очередь жалобы и объективные данные (физикальные), которые потом дополняют результатами лабораторных и/или инструментальных исследований. Часто можно прочесть: пациент presented с жалобами на [.......], симптомами [....], при проведении ...[анализов исследований]... было выявлено ....

Larisa Horback Feb 12, 2016:

@ Evgeniy Clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient.
Clinical manifestations that can be either objective when observed by a physician, or subjective when perceived by the patient.

Ятоже так думала, потом решила, что это синонимы.. Вы меня заставили все-таки разобраться в таких тонкостях:)
Если пациент жалуется врачу и врач видит симптоматику, то тогда manifestation, а если ставится диагноз по результатам анализов, то тогда presentation.
Если прочитать предложение, то можно понять, что это наблюдение врача, а не результаты анализов, поэтому я склоняюсь все-таки к версии manifestation.

Evgeni Kushch Feb 12, 2016:

or patient presented with symptoms [and signs] of TIA

Evgeni Kushch Feb 12, 2016:

O would write as well [clinical] symptoms and signs of TIA were observed

Evgeni Kushch Feb 12, 2016:

А про presentation почему все забыли? :-) patient presented, clinical presentation

http://medical-dictionary.thefreedictionary.com/clinical pre...

Larisa Horback Feb 12, 2016:

"Clinical" manifestations of a disease mean those that can be determined by History (talking to the patient) and Examination (observing the patient, including with some simple tools like a stethoscope or thermometer).

For example, you might diagnose pneumonia clinically by talking to the patient and finding they have got sick quickly, feel hot one minute and cold the next, have trouble walking up stairs and are coughing a lot of discoloured phlegm. On clinical examination they have a fever, are breathing rapidly and have lung sounds consistent with consolidation. You deduce or diagnose clinically that they have pneumonia.

You might then confirm your "clinical" diagnosis with (non clinical) tests such as a chest Xray, sputum culture and blood gases.

Maksym Panchenko (asker) Feb 12, 2016:

Из выписного эпикриза. И это, в общем, и есть все предложение.

Вообще, "clinical manifestations" из ответа rns думаю подойдет.

Erzsébet Czopyk Feb 12, 2016:

eto ne ta informacija, sto men nuzhno. I nado celoje predlozhenije. Iz kakogo dokumenta?

Maksym Panchenko (asker) Feb 12, 2016:

Not sure it would be very helpful, but here you go: "В январе 2013 отмечалась клиника ТИА".

Erzsébet Czopyk Feb 12, 2016:

please, give any context which makes possible to give you a correct solution