Nov 17, 2016 16:05
7 yrs ago
1 viewer *
français term
Marqueurs spécifiques de prise
français vers anglais
Médecine
Médecine (général)
From a medical report of a young child admitted for gene therapy, with a diagnosis of X-linked chronic granulomatous disease. It is a heading:
Marqueurs spécifiques de prise: DHR: 20% (XX/XX) et 28% (XX/XX).
NB. "XX" are dates.
So what kind of markers are these? What does "de prise" mean here?
DHR = Dihydrorhodamine
Thank you.
Marqueurs spécifiques de prise: DHR: 20% (XX/XX) et 28% (XX/XX).
NB. "XX" are dates.
So what kind of markers are these? What does "de prise" mean here?
DHR = Dihydrorhodamine
Thank you.
Proposed translations
(anglais)
4 +2 | specific uptake markers | Sue Davis |
4 | specific marker test/specific marker screen | liz askew |
3 | specific markers of X intake | Drmanu49 |
Proposed translations
+2
1 heure
Selected
specific uptake markers
The marker is Dihydrorhodamine. This is a fluorescent marker of superoxide generation by neutrophils. In this condition, there is defective production of superoxide by neutrophils and uptake of the marker is reduced. The percentages may refer to the percentage of neutrophils taking in the fluorescent marker See:
https://www.ncbi.nlm.nih.gov/pubmed/8223655
https://books.google.co.uk/books?id=U4jqbShpfioC&pg=PA444&lp...
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Note added at 1 hr (2016-11-17 17:44:48 GMT)
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I should have also said that superoxide production is thought to play a role in the antibacterial action of neutrophils. Therefore reduced DHR uptake resulting from reduced superoxide production is an indication of the impairment in neutrophil immune function.
https://www.ncbi.nlm.nih.gov/pubmed/8223655
https://books.google.co.uk/books?id=U4jqbShpfioC&pg=PA444&lp...
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Note added at 1 hr (2016-11-17 17:44:48 GMT)
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I should have also said that superoxide production is thought to play a role in the antibacterial action of neutrophils. Therefore reduced DHR uptake resulting from reduced superoxide production is an indication of the impairment in neutrophil immune function.
Peer comment(s):
agree |
Anne Schulz
: great research (or knowledge :-)
22 minutes
|
thank you!
|
|
agree |
Rachel Fell
16 heures
|
thank you!
|
4 KudoZ points awarded for this answer.
Comment: "This is excellent. Thank you very much."
45 minutes
specific marker test/specific marker screen
Best guess
must be "prise de sang", how else would they test the markers?
What Is the Multiple Marker Test? - KidsHealth
kidshealth.org/en/parents/triple-screen.html
Expectant mothers usually are offered a blood test called the multiple marker test, sometimes called a triple screen or a quad screen. Find out what it measures.
Raised inflammatory markers | The BMJ
www.bmj.com/content/344/bmj.e454
by J Watson - 2012 - Cited by 26 - Related articles
3 Feb 2012 - Raised levels of inflammatory markers may be found in many other conditions, ... The classic conditions for which testing may be useful are ...
Triple Marker Screen Test | Definition and Patient Education - Healthline
www.healthline.com › Pregnancy › Home
14 Oct 2016 - The triple marker screen test analyzes how likely an unborn baby is to have certain genetic disorders. It is also known as a multiple marker test.
Pregnancy and the Quad Marker Screen - WebMD
www.webmd.com › Pregnancy › Guide
19 Sep 2016 - WebMD tells you why you might choose to have a quad marker screen, a blood test used during pregnancy that may reveal birth defects in the ...
must be "prise de sang", how else would they test the markers?
What Is the Multiple Marker Test? - KidsHealth
kidshealth.org/en/parents/triple-screen.html
Expectant mothers usually are offered a blood test called the multiple marker test, sometimes called a triple screen or a quad screen. Find out what it measures.
Raised inflammatory markers | The BMJ
www.bmj.com/content/344/bmj.e454
by J Watson - 2012 - Cited by 26 - Related articles
3 Feb 2012 - Raised levels of inflammatory markers may be found in many other conditions, ... The classic conditions for which testing may be useful are ...
Triple Marker Screen Test | Definition and Patient Education - Healthline
www.healthline.com › Pregnancy › Home
14 Oct 2016 - The triple marker screen test analyzes how likely an unborn baby is to have certain genetic disorders. It is also known as a multiple marker test.
Pregnancy and the Quad Marker Screen - WebMD
www.webmd.com › Pregnancy › Guide
19 Sep 2016 - WebMD tells you why you might choose to have a quad marker screen, a blood test used during pregnancy that may reveal birth defects in the ...
54 minutes
specific markers of X intake
Redox Biochemistry - Page 275 - Résultats Google Recherche de Livres
https://books.google.fr/books?isbn=0470177322 - Traduire cette page
Ruma Banerjee - 2007 - Science
Limitations to the use of DCF fluorescence as a specific marker for intracellular ... is dihydrorhodamine 123 (DHR 123), which can be oxidized to the fluorophore ...
https://books.google.fr/books?isbn=0470177322 - Traduire cette page
Ruma Banerjee - 2007 - Science
Limitations to the use of DCF fluorescence as a specific marker for intracellular ... is dihydrorhodamine 123 (DHR 123), which can be oxidized to the fluorophore ...
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