„Kliničko ispitivanje otvorenog tipa u kojem sudjeluju ispitanici dobi između 6 i 18 godina starosti koji pate od bolova za čije su liječenje potrebni opioidi s produljenim oslobađanjem, a kojim se procjenjuje sigurnost i djelotvornost tapentadola s produljenim oslobađanjem naspram morfina s produljenim oslobađanjem, nakon čega slijedi otvoreni nastavak ispitivanja“

/“An open label trial, enrolling subjects aged 6 years to less than 18 years suffering from pain requiring prolonged release opioid treatment, to evaluate the safety and efficacy of tapentadol PR versus morphine PR, followed by an open label extension“/



baseline value > početna vrijednost
open-label study > otvoreno ispitivanje
http://www.halmed.hr/fdsak3jnFsk1Kfa/ostale_stranice/Preporu...



The mean changes from open-label baseline (ie, the beginning of the 6-month study) to Week 24 in weight (in pounds), glucose, and lipids, as well as the median change from open-label baseline to Week 24 in prolactin, are presented in Table 5.23 Patients received LATUDA as monotherapy or as adjunctive therapy with lithium or valproate in the short-term studies and contin- ued on LATUDA in the longer-term study.23

http://bipolardepression.currentpsychiatry.com/wp-content/up...