Aug 17, 2017 21:59
6 yrs ago
6 viewers *
English term

local reading

English Medical Medical: Pharmaceuticals
What is the exact meaning of the term "local reading" in the following: At the time of study treatment code unblinding, patients who choose to receive open-label [name of test drug] will have a start of open-label treatment visit and will visit the study centre every X weeks until metastasis is seen by local reading.
This is from a clinical trial protocol.

Thanks for your help!
Votes to reclassify question as PRO/non-PRO:

Non-PRO (2): writeaway, Yvonne Gallagher

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Responses

+5
4 hrs
Selected

local reading

It means a local reading in opposite to a central reading. The local reading is performed in the investigators site. Nevertheless, for some procedures like imagenologic studies, EKG, etc., it is mandatory to perform a central reading so just one trained (and blinded) person performs the evaluations. I hope I explained it clearly.

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Note added at 4 hrs (2017-08-18 02:50:24 GMT)
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PS: The central reading is done by somebody assigned by the Sponsor, unrelated to the investigative sites.
Note from asker:
Thank you, Rosario. It is indeed the opposite of a central reading and is carried out at the study site, as I found out in another part of the document.
Peer comment(s):

agree Tina Vonhof (X) : Good explanation.
1 hr
Thanks! :)
agree Daryo
12 hrs
agree Majid Wahab : Good explanation
5 days
agree acetran
20 days
agree Jörgen Slet
38 days
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Selected automatically based on peer agreement."
+2
9 mins

the on-site (local) analysis department

I'm a native speaker but even so not sure about this. I think it could refer to the department resposible for interpreting the results

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Note added at 10 mins (2017-08-17 22:09:44 GMT)
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"reading" would indicate "analysis" or "interpretation"

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Note added at 11 mins (2017-08-17 22:10:30 GMT)
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maybe your full context will help you further
Peer comment(s):

agree Sabine Akabayov, PhD : or analysis in the local laboratory
12 mins
vielen Dank Sabine ... ich bin mir überhaupt nicht sicher in diesem Zusammenhang, aber scheint zu passen thanks Sabine and not sure at all if this fits in the context but seems to
agree acetran
20 days
Something went wrong...
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