May 6, 2018 20:52
6 yrs ago
11 viewers *
Spanish term
United States
SMP G2
Spanish to English
Medical
Medical (general)
Lung cancer reports
This term is included in a report from Mexico by an oncologist, for a patient with lung cancer. Lots of idiosyncratic doctor shorthand, abbreviations, etc. There is no real immediate context for this term, but I'm including a considerable chunk of the report below:
X, masculino de 74 años con el Dx de Carcinoma epidermoide moderadamente diferenciado. EC IIIA por T3 tumor a menos de 2 cm de la carina N2 por adenopatías mediastinales ipsilateral, QT de inducción 2 ciclos Carbo Paclitaxel QT/RT 34Fx con 6 semanas carbo Paclitaxel, finalizo el dia 30 de mayo 2017.
Actual acude a QT de consolidación por 2 ciclos. lndicamos primer ciclo de carbo Paclitaxel. Acude a valorar el ciclo numero 2 de consolidación
Se Refiere Fatigado, entumecimiento de manos y pies
Toxicidades. ***SMP G2***, Fatiga g1, Debilidad g1,
Signos vitales TA 131/65 FC 66 FR 19 SO2 96% Peso 76.5 77.5 Talla 1.68 SC 1.90 A la EF en regulares condiciones generales, no datos de insuficiencia respiratoria, campos pulmonares con murmullo vesicular normal, no sibilancias.
I think the "G2" (& "g1" in following terms) are from standard terminology for the phases of the cell cycle (?). But I haven't been able to run anything down on "SMP".
Any help will be greatly appreciated.
X, masculino de 74 años con el Dx de Carcinoma epidermoide moderadamente diferenciado. EC IIIA por T3 tumor a menos de 2 cm de la carina N2 por adenopatías mediastinales ipsilateral, QT de inducción 2 ciclos Carbo Paclitaxel QT/RT 34Fx con 6 semanas carbo Paclitaxel, finalizo el dia 30 de mayo 2017.
Actual acude a QT de consolidación por 2 ciclos. lndicamos primer ciclo de carbo Paclitaxel. Acude a valorar el ciclo numero 2 de consolidación
Se Refiere Fatigado, entumecimiento de manos y pies
Toxicidades. ***SMP G2***, Fatiga g1, Debilidad g1,
Signos vitales TA 131/65 FC 66 FR 19 SO2 96% Peso 76.5 77.5 Talla 1.68 SC 1.90 A la EF en regulares condiciones generales, no datos de insuficiencia respiratoria, campos pulmonares con murmullo vesicular normal, no sibilancias.
I think the "G2" (& "g1" in following terms) are from standard terminology for the phases of the cell cycle (?). But I haven't been able to run anything down on "SMP".
Any help will be greatly appreciated.
Proposed translations
(English)
| 3 +4 | hand-foot syndrome - grade2 |
Helena Chavarria
|
Proposed translations
+4
20 mins
Helena Chavarria
Spain
Spain
Native in English
Spain
Striving for excellence
Native in: English (Variant: British) 
Works in: Spanish to English, Catalan to English
Related KudoZ points
:
381
Selected
hand-foot syndrome - grade2
Resultados. Se incluyeron 93 pts (45 BC/48 CRC) tratados previamente. 31 presentaron toxicidad grado 3-4: síndrome mano-pie (SMP) 15%,
https://www.seom.org/seomcms/images/stories/recursos/sociosy...
Page 6
Frequency of toxicity in descending order were fatigue, hand-foot syndrome (palmar-plantar erythrodysesthesia, PPE), diarrhoea and nausea that inflicted on the majority of patients and often led to dose reduction and discontinuation of treatment.
https://www.tandfonline.com/doi/pdf/10.1080/0284186050037521...
Page 2
grade definition
G1 minimal skin changes or dermatitis (e.g., erythema, edema, or hyperkeratosis) without pain
G2 skin changes (e.g., peeling, blisters, bleeding, edema, or hyperkeratosis) with pain; limitinginstrumental activities daily living
G3 severe skin changes (e.g., peeling, blisters, bleeding, edema, or hyperkeratosis) with pain; limiting self care activities of daily living
Page 3
Those patients who were in contact with their oncology nurses and followed the recommendations had fiftyfold lower lower risk of developing hand-foot syndrome G2 or G3 as compared to the patients who did not cooperate.
http://www.wple.net/plek/numery_2016/numer-7-2016/460-464.pd...
Many of the published clinical trials of agents associated with hand-foot syndrome were initiated prior to the introduction of a standard grading scheme. In capecitabine trials, hand-foot syndrome has been graded 1 to 3, based on functional criteria: Grade 1 was defined as numbness, dysesthesia/paresthesia, tingling, painless swelling, or erythema not disrupting normal activities; grade 2 was defined as painful erythema with swelling that disrupts daily activities; and grade 3 was defined as moist desquamation, ulceration, blistering, severe pain, or any symptoms leading to an inability to perform daily activities.
http://www.cancernetwork.com/breast-cancer/coming-grips-hand...
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Note added at 5 days (2018-05-12 16:46:02 GMT) Post-grading
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Tom, I'm glad to have helped. Thank you for your kind words!
https://www.seom.org/seomcms/images/stories/recursos/sociosy...
Page 6
Frequency of toxicity in descending order were fatigue, hand-foot syndrome (palmar-plantar erythrodysesthesia, PPE), diarrhoea and nausea that inflicted on the majority of patients and often led to dose reduction and discontinuation of treatment.
https://www.tandfonline.com/doi/pdf/10.1080/0284186050037521...
Page 2
grade definition
G1 minimal skin changes or dermatitis (e.g., erythema, edema, or hyperkeratosis) without pain
G2 skin changes (e.g., peeling, blisters, bleeding, edema, or hyperkeratosis) with pain; limitinginstrumental activities daily living
G3 severe skin changes (e.g., peeling, blisters, bleeding, edema, or hyperkeratosis) with pain; limiting self care activities of daily living
Page 3
Those patients who were in contact with their oncology nurses and followed the recommendations had fiftyfold lower lower risk of developing hand-foot syndrome G2 or G3 as compared to the patients who did not cooperate.
http://www.wple.net/plek/numery_2016/numer-7-2016/460-464.pd...
Many of the published clinical trials of agents associated with hand-foot syndrome were initiated prior to the introduction of a standard grading scheme. In capecitabine trials, hand-foot syndrome has been graded 1 to 3, based on functional criteria: Grade 1 was defined as numbness, dysesthesia/paresthesia, tingling, painless swelling, or erythema not disrupting normal activities; grade 2 was defined as painful erythema with swelling that disrupts daily activities; and grade 3 was defined as moist desquamation, ulceration, blistering, severe pain, or any symptoms leading to an inability to perform daily activities.
http://www.cancernetwork.com/breast-cancer/coming-grips-hand...
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Note added at 5 days (2018-05-12 16:46:02 GMT) Post-grading
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Tom, I'm glad to have helped. Thank you for your kind words!
4 KudoZ points awarded for this answer.
Comment: "Great answer as usual, Helena. Well-explained, clear, brief & to the point, with helpful references. Thanks a lot."
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