Jul 28, 2020 21:44
3 yrs ago
31 viewers *
English term

orthogonal

English to Spanish Medical Medical: Pharmaceuticals Iron levels in the brain-Conference
My question is whether the above term is best translated as 'perpendicular', 'ortogonal' or 'independiente' in the following context:

“While certain brain regions did not have increased iron, the iron burden, within this normal range, was still associated with cognitive decline".
“This confirms iron as a neurochemical factor critical for cognitive deterioration in AD but orthogonal to plaques and tangles.”

Thank you
Proposed translations (Spanish)
4 +3 independiente
4 perpendicular

Discussion

Chema Nieto Castañón Jul 28, 2020:
Orthogonal
statistically independent
https://www.merriam-webster.com/dictionary/orthogonal
liz askew Jul 28, 2020:
Search Results
Web results

Plaque and tangle imaging and cognition in normal ... - NCBIwww.ncbi.nlm.nih.gov › pmc › articles › PMC2891885
11 Nov 2008 - Amyloid plaques and tau neurofibrillary tangles, the pathological hallmarks ... All but seven of the subjects included in the current study also were reported ... Among the AD patients, cognitive impairment prevented two subjects from ... Thickness and PET signal are ***orthogonal (not correlated)***except in very ...

Proposed translations

+3
19 mins
Selected

independiente

I found this sentence in an article (https://onlinelibrary.wiley.com/doi/full/10.1002/mrm.21586)

However, the lack of a correlation between plaque load and iron concentrations suggests that the increases in AD brain iron are not strongly related to the deposition and accumulation of amyloid plaques.

Thus, independiente would be the best translation

Peer comment(s):

agree liz askew
9 mins
agree Chema Nieto Castañón : ... estadísticamente independiente de; pero estadísticamente no se correlaciona con.
28 mins
agree Ninoslav Matijevic : Tienes mi consentimiento. Independiente - Independent (no influence to); Ortogonal - "At right angle" or "Statistically independent"
3 hrs
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4 KudoZ points awarded for this answer. Comment: "thank you"
17 mins

perpendicular

Espero haberte ayudado!
Peer comment(s):

neutral Chema Nieto Castañón : Hola Nelson, no consigo ver qué relación pueda tener con el tema que nos ocupa la orientación perpendicular de unas fibrillas o el gradiente perpendicular a la corriente eléctrica de distintos agentes en una electroforesis...
35 mins
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