This question was closed without grading. Reason: Answer found elsewhere
Aug 1, 2020 22:41
3 yrs ago
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English term
SRL-use
English to German
Medical
Medical: Pharmaceuticals
This s a letter sent by a pharmaceutical company to a doctor about a medicine. They are enclosing the following:
-SRL- Use in Urological Conditions
-SmPC of [name of drug]
What is "SRL use"?
-SRL- Use in Urological Conditions
-SmPC of [name of drug]
What is "SRL use"?
Proposed translations
(German)
| 4 | Sirolimus (Rapamycin) |
Brent Sørensen
|
Proposed translations
22 mins
Brent Sørensen
Germany
Germany
Native in English
Specializes in field
Germany
Native EN|PhD|Parmaceuticals|Medical
Native in: English (Variants: US, UK) 
Works in: German to English, Danish to English, English, and 1 more.
Sirolimus (Rapamycin)
It’s the name of a drug
https://de.wikipedia.org/wiki/Sirolimus
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Note added at 24 mins (2020-08-01 23:06:06 GMT)
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Summary
In addition to an analysis of the final results of phase I/II and phase III clinical trials of sirolimus (SRL), this review focuses on the recent results of several studies in renal transplantation, which include diverse combinations of SRL with other immunosuppressive agents.
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1432-2277...
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Note added at 6 hrs (2020-08-02 04:50:26 GMT)
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Are you sure it’s not sirolimus. This is used for renal transplants, which is covered by urology.
Here is a list of other possibilities:
http://acronymsandslang.com/meaning-of/medicine-and-science/...
I wouldn’t use "SRL Anwendung” unless you are absolutely sure that the same abbreviation is used in Germany.
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Note added at 10 hrs (2020-08-02 08:59:38 GMT)
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sarcin/ricin loop
https://www.nature.com/articles/ncomms3796
German would be Sarcin-Ricin-Schleife (SRL)
In der eukaryotischen 28S-ribosomalen RNA enthält die Sarcin-Ricin-Schleife (SRL) ein Motiv der Schleife E, das das AA-Paar, das gewölbte G-, UA-Paar und das GA-Paar 19, 20 enthält ; Die effektive Abweichung zwischen der Kristallstruktur von SRL und dem IIId-Loop-E-Motiv der HCV-IRES-Domäne beträgt 1, 15 Å.
https://sarlpromotech.com/structures-two-rna-domains-essenti...
So that means you can leave it as SRL if this is the right definition.
https://de.wikipedia.org/wiki/Sirolimus
--------------------------------------------------
Note added at 24 mins (2020-08-01 23:06:06 GMT)
--------------------------------------------------
Summary
In addition to an analysis of the final results of phase I/II and phase III clinical trials of sirolimus (SRL), this review focuses on the recent results of several studies in renal transplantation, which include diverse combinations of SRL with other immunosuppressive agents.
https://onlinelibrary.wiley.com/doi/full/10.1111/j.1432-2277...
--------------------------------------------------
Note added at 6 hrs (2020-08-02 04:50:26 GMT)
--------------------------------------------------
Are you sure it’s not sirolimus. This is used for renal transplants, which is covered by urology.
Here is a list of other possibilities:
http://acronymsandslang.com/meaning-of/medicine-and-science/...
I wouldn’t use "SRL Anwendung” unless you are absolutely sure that the same abbreviation is used in Germany.
--------------------------------------------------
Note added at 10 hrs (2020-08-02 08:59:38 GMT)
--------------------------------------------------
sarcin/ricin loop
https://www.nature.com/articles/ncomms3796
German would be Sarcin-Ricin-Schleife (SRL)
In der eukaryotischen 28S-ribosomalen RNA enthält die Sarcin-Ricin-Schleife (SRL) ein Motiv der Schleife E, das das AA-Paar, das gewölbte G-, UA-Paar und das GA-Paar 19, 20 enthält ; Die effektive Abweichung zwischen der Kristallstruktur von SRL und dem IIId-Loop-E-Motiv der HCV-IRES-Domäne beträgt 1, 15 Å.
https://sarlpromotech.com/structures-two-rna-domains-essenti...
So that means you can leave it as SRL if this is the right definition.
Note from asker:
| Hi Brent, and thanks for your input. I'm afraid that sirolimus does no fit the context at all. Do you think I could just leave it as is in German? (as SRL-Anwendung)? |
Discussion
Rapamycin is discussed in context with bladder outlet obstruction (see e.g. https://pubmed.ncbi.nlm.nih.gov/23313213/), but this is certainly not an established indication which would be described in the SmPC. On the other hand, I can't think of any other procedure, technique or substance which could be abbreviated SRL. You may have to add a translator's note (unless someone else comes up with a brilliant idea).
So, what about the subject of this letter – is the pharmaceutical company promoting some technique or effect "SRL" which can be achieved by their drug? or warning about some side effect from "SRL" which can be managed by their drug? or comparing their drug against some competitor "SRL" for use in urology?...