Glossary entry

English term or phrase:

GTP pocket

Portuguese translation:

local de ligação da GTP (guanosina trifosfato)

Added to glossary by Matheus Chaud
Nov 30, 2021 18:19
2 yrs ago
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English term

GTP pocket

English to Portuguese Medical Patents
The prevalent G12C mutation drives tumor growth and metastasis and has become an important validated target for therapy especially in lung and colorectal cancer.

Targeting the GTP pocket of Kras in the switch-II region, which has made Kras druggable, enables the development of more potent and potentially effective inhibitors.
Change log

Jan 9, 2022 01:11: Matheus Chaud Created KOG entry

Proposed translations

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local de ligação da GTP (guanosina trifosfato)


GTP = Guanosine triphosphate = GTP = trifosfato de guanosina (ou guanosina trifosfato)
https://www.google.com/search?q="GTP" "guanosina trifosfato"

pocket = local de ligação, sítio de ligação:
https://www.proz.com/kudoz/english-to-portuguese/medical-gen...
Peer comment(s):

agree Wanda de Melo : Trifosfato de Guanosina e local de fixação de O2 nas moléculas de hemoglobina; bolsas do heme.
28 mins
Obrigado, Wanda!
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