Glossary entry

Norwegian term or phrase:

komplementfunksjon

English translation:

complement activation

Added to glossary by Alison Waddington
Aug 29, 2023 10:04
9 mos ago
13 viewers *
Norwegian term

komplementfunksjon

Norwegian to English Medical Medical (general) Medical report
Hei! I can't find any appropriate resources for this term, can it simply translate as 'complement function?'

The patient has fibromyalgia, joint pain and fatigue as well as hyperparathyroidism and hypogammaglobulinemia, if this helps.

Please confirm if so, and if not, I'd be grateful for further pointers to its meaning!

Mvh
Alison.
Proposed translations (English)
4 +1 complement activation
2 action of complement

Discussion

Alison Waddington (asker) Aug 29, 2023:
More context/source text Hi Eodd, of course I'll provide what I can. The medical report begins by stating that the patient has both hyperparathyroidism and hypogammaglobulinemia, "i tillegg sterkt nedsatt komplementsfunksjon. Symptomer i form av invalidiserende utmattelse .. og generelle kroppsmerter". I know this doesn't appear to be much, but does this shed any light at all? - Alison.
eodd Aug 29, 2023:
Can you provide more context, or the source text?

Proposed translations

+1
1 hr
Selected

complement activation

"Severely reduced complement activation or "Severe complement deficiency" is what I would use for the translation of "sterkt nedsatt komplementsfunksjon"

The complement system consists of almost 60 proteins, approximately 30 of which are circulating blood proteins that work together to promote immune and inflammatory responses. Complement tests measure the amount or activity of complement proteins in the blood.

The complement system’s principal role is to help identify, destroy and remove foreign pathogens like bacteria and viruses, as well as damaged “self” materials (e.g., cells and proteins). The complement system is so named because it “complements” or aids the natural body defenses, such as antibodies. So, the complement system is also activated when the body makes antibodies, whether against itself or foreign invaders. The body makes antibodies against its own tissues that it thinks are foreign (autoantibodies) in various autoimmune diseases.

https://www.testing.com/tests/complement/

https://metodebok.no/index.php?action=topic&item=bVMtjQB4
Peer comment(s):

agree Michele Fauble
6 hrs
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4 KudoZ points awarded for this answer. Comment: "Thanks, Eodd!"
5 hrs

action of complement

i tillegg sterkt nedsatt komplementsfunksjon : in addition serious depletion of the complement component.

hyperparathyroidism : rings loud (Chernobyl) radiation-induced bells, though the causation of the patient's aka client's condition isn't spelt out.
Example sentence:

The most important action of complement is to facilitate the uptake and destruction of pathogens by phagocytic cells.

The results indicate that complement depletion in vivo reduced the binding of IC to erythrocytes.

Note from asker:
Thanks for your contribution, Adrian; very enlightening!
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