Glossary entry

French term or phrase:

critère d\'orientation

English translation:

with no indications whether to attribute it (the side effect) to A or B

Added to glossary by joanna menda
Sep 10, 2023 14:05
8 mos ago
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French term

critère d'orientation

French to English Medical Medical (general) hospitalization report
Hi,
I have the following: "L'hypothèse privilégiée actuellement est plutôt un épanchement induit par les traitements, sans critère d'orientation pour le PONATINIB ou L'AZACYTIDINE."
Thanks
Joanna

Discussion

philgoddard Sep 12, 2023:
Daryo I said all this 22 hours ago.
Daryo Sep 11, 2023:
I don't think that "guidelines" are missing they do exist - MUST exist. You don't get drugs let loose on patients without any "guidelines" about how and when to use them.

What is missing is information about the specific patient at the specific point in time, patient information that would help to decide which "guideline" is applicable i.e. which of this two drugs is more suitable for the patient.

Or, if both drugs were given in past, the "missing information" is needed to decide which drug is causing the side effect. Then

sans critère d'orientation pour le PONATINIB ou L'AZACYTIDINE
would mean
there is nothing to indicate which one of the two caused the épanchement.

i.e. none of the patient's exam results can be used as "distinguishing criteria" to decide which one caused the side effect.
joanna menda (asker) Sep 10, 2023:
@phil. I agree 100%. Maybe guideline on what to do next if the effusion is caused by these drugs. For instance, lower the dose, discontinue the drug, stop the drug for a short period....
philgoddard Sep 10, 2023:
But you wouldn't prescribe a drug without giving guidelines, so I don't think that's the answer.
joanna menda (asker) Sep 10, 2023:
@Phil. Yes, these are drugs given to patient and their hypothesis is that the effusion is caused by the treatments. I think Bartosz suggestion of "guidelines" is good. "No guidelines were given..."
philgoddard Sep 10, 2023:
Are they the drugs the patient has been given? If so, could it mean we don't know which one caused it?
Epanchement is effusion.

Proposed translations

+1
1 day 7 mins
French term (edited): sans critère d'orientation pour A ou B
Selected

with no indications whether to attribute it (the side effect) to A or B

You have to look at the whole of

"sans critère d'orientation pour A ou B"

Peer comment(s):

agree SafeTex
5 days
Thanks!
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4 KudoZ points awarded for this answer. Comment: "Thanks!"
19 mins

Guiding criterion/guidelines/cue

Guiding criterion/guidelines/cue or sth similiar
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2 hrs

benchmark as a pointer

Pointer - not an English dog breed in this instance, rather an indication of a suitable medication or 'drug'.

... sans critère d'orientation pour le PONATINIB ou L'AZACYTIDINE" : with no benchmark as a pointer to Ponatinib or Azacytidine (as 'inhibitors').

Example sentence:

We need to go a step further and determine the proper benchmark for the use of prescription drugs

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Reference comments

8 hrs
Reference:

with no criteria to pinpoint/implicate/point towards

for some reason I unable to post a contribution

with no criteria to implicate/point towards


xxxxxxx
being responsible for pleural effusion

i.e. no evidence to hold these drugs responsible for pleural effusion


. Of the case reports in the literature, pleuropericardial effusions with azacitidine are generally seen early in the treatment course. [14][15][16][17]27 This case report illustrates that pleuropericardial effusion can potentially happen at any time during the treatment of the MDS patient with azacitidine. This report adds to the current literature of possible azacitidineinduced effusions and increases awareness of this rarely reported adverse event in FAERS. .
Peer comments on this reference comment:

agree Daryo : you got to the same conclusion as myself.
15 hrs
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