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  3. Medical: Cardiology

bone-avid compounds

Russian translation: изотопы, накапливающиеся в костях

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:bone-avid compounds
Russian translation:изотопы, накапливающиеся в костях
Entered by: Andrew Tishin

16:39 Jul 24, 2022
English to Russian translations [PRO]
Medical - Medical: Cardiology / сердечная недостаточность
English term or phrase: bone-avid compounds
The use of 99m Tc bone-avid compounds for bone scintigraphy allows for noninvasive diagnosis of ATTR-CM. 99m Tc compounds include PYP, 3,3-diphosphono1,2-propanodicarboxylic acid, and hydromethylene diphosphonate, and PYP is used in the United States. In the absence of a light-chain abnormality, the 99m Tc-PYP scan is diagnostic of ATTR-CM if there is grade 2/3 cardiac uptake or an H/CL ratio of >1.5. In fact, the presence of grade 2/3 cardiac uptake in the absence of a monoclonal protein in serum or urine has a very high specificity and positive predictive value for ATTR-CM (7). SPECT is assessed in all positive scans to confirm that uptake represents myocardial retention of the tracer and not blood pool or rib uptake signal (12).

(из раздела Diagnosis of Cardiac Amyloidosis)
Andrew Tishin
Russian Federation
Local time: 21:23
изотопы, накапливающиеся в костях
Explanation:
https://www.medarhive.ru/jour/article/view/1106?locale=ru_RU
Амилоидоз сердца: взгляд терапевта и кардиолога
там есть русский и английский варианты статьи

В частности, в русском варианте в таблице 7 читаем: "Изотопы, накапливающиеся в костях, в первую очередь использующиеся в США/
Bone avid tracers primarily used in the United States

Т.е., можно перевести как "изотопы (соединения/вещества), накапливающиеся в костях".
Selected response from:

Marlin31
Russian Federation
Local time: 21:23
Grading comment
Благодарю!
4 KudoZ points were awarded for this answer



Summary of answers provided
3изотопы, накапливающиеся в костях
Marlin31
Summary of reference entries provided
liz askew

  

Answers


4 hrs   confidence: Answerer confidence 3/5Answerer confidence 3/5
изотопы, накапливающиеся в костях


Explanation:
https://www.medarhive.ru/jour/article/view/1106?locale=ru_RU
Амилоидоз сердца: взгляд терапевта и кардиолога
там есть русский и английский варианты статьи

В частности, в русском варианте в таблице 7 читаем: "Изотопы, накапливающиеся в костях, в первую очередь использующиеся в США/
Bone avid tracers primarily used in the United States

Т.е., можно перевести как "изотопы (соединения/вещества), накапливающиеся в костях".

Marlin31
Russian Federation
Local time: 21:23
Native speaker of: Native in RussianRussian
PRO pts in category: 40
Grading comment
Благодарю!
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Reference comments


32 mins
Reference

Reference information:
https://pubmed.ncbi.nlm.nih.gov/789010/

Technetium-99m labeled radiopharmaceuticals are the currently accepted agents of choice for skeletal imaging. Their introduction in 1971 literally initiated a new era in clinical bone scanning. The development of techniques for reducing Tc(VII) with Sn(II) provided the means for complexing this useful radionuclide with various *****phosphorus-containing compounds which were already known to be avid bone seekers****.

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Note added at 34 mins (2022-07-24 17:13:46 GMT)
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Neuroblastoma Iodine-131-Metaiodobenzylguanidine and ...
https://citeseerx.ist.psu.edu › viewdoc › download
PDF
by BL Shulkin · 1992 · Cited by 89 — Neuroblastoma. Iodine-131-Metaiodobenzylguanidine and Bone Scintigraphy for the Detection of ... tiple ****bone-avid agents**** have been shown to

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Note added at 45 mins (2022-07-24 17:24:53 GMT)
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ALSO known as



Cardiac Scintigraphy With Technetium-99m-Labeled Bone ...
https://www.sciencedirect.com › science › article › pii
by M Hanna · 2020 · Cited by 70 — Cardiac Scintigraphy With Technetium-99m-Labeled ****Bone-Seeking Tracers**** for ... Over the past 15 years, 3 technetium-labeled radiotracers

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Note added at 52 mins (2022-07-24 17:32:13 GMT)
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Bone-seeking radiopharmaceuticals based on phosphonic acids and 68Ga (review),Остеотропные радиофармацевтические препараты на основе фосфоновых кислот и 68Ga (обзор)

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Note added at 55 mins (2022-07-24 17:34:47 GMT)
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https://www.elibrary.ru/item.asp?id=42594862

КЛЮЧЕВЫЕ СЛОВА:

ГАЛЛИЙ-68, ФОСФОНОВЫЕ КИСЛОТЫ, БИСФОСФОНАТЫ, ОСТЕОТРОПНЫЕ РАДИОФАРМПРЕПАРАТЫ, КОСТНЫЕ МЕТАСТАЗЫ, РАДИОНУКЛИДНАЯ ДИАГНОСТИКА, ПОЗИТРОННАЯ ЭМИССИОННАЯ ТОМОГРАФИЯ, ЭТИЛЕНДИАМИНТЕТРА(МЕТИЛЕНФОСФОНОВАЯ КИСЛОТА), 1,4,7,10-ТЕТРААЗАЦИКЛОДОДЕКАН-1,4,7,10-ТЕТРАКИС(МЕТИЛЕНФОСФОНОВАЯ КИСЛОТА), DOTA, NOTA, GALLIUM-68, PHOSPHONIC ACIDS, BISPHOSPHONATES, BONE-SEEKING RADIOPHARMACEUTICALS, BONE METASTASES, RADIONUCLIDE DIAGNOSIS, POSITRON EMISSION TOMOGRAPHY, ETHYLENEDIAMINE TETRA(METHYLENE PHOSPHONIC ACID), 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAKIS(METHYLENE PHOSPHONIC ACID)

liz askew
United Kingdom
Specializes in field
Native speaker of: Native in EnglishEnglish
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